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2 min read

Top 6 Signs and Symptoms of Prostate Disorder



The prostate is a small gland that is part of the male reproductive system. It's supposed to be about the shape and size of a walnut. It is located below the bladder and in front of the rectum. It surrounds a section of the urethra, the tube in your penis that transports urine from your bladder. The prostate helps make some of the fluid in semen, which carries sperm from men's testicles when ejaculating.


Your prostate may enlarge as you grow older. Most guys experience it as a natural part of ageing. The enlarged prostate might constrict the tube since it surrounds part of the urethra. As a result, problems with the prostate can affect both sexual and urine functioning. How do you know whether you are having a prostate problem? Watch out for the signs and symptoms below.


Top 6 Signs and Symptoms of Prostate Disorder


1. Have a weak urine stream - Benign prostatic hyperplasia (BPH) is the most common cause of this problem in men. When there is a problem with urine flow, it usually means that the bladder is not emptying properly. This happens with BPH because the enlarged prostate blocks the urethra, which is the tube that drains urine from the penis.



2. Frequent night urine trip - Nocturia is a condition in which you wake up frequently in the middle of the night to urinate. It commonly happens in men with enlarged prostate or BPH. Because the prostate is enlarged, extra pressure is applied to the urethra – the tube through which urine flows from the bladder and out of the body – and urine is retained in the bladder. Nocturia is a common and bothersome symptom in men with an enlarged prostate gland.



3. Get frequent pain or discomfort in your lower abdomen or pain while passing urine - You could have prostate inflammation (prostatitis) If you are constantly experiencing pain around the base of the penis and behind the scrotum, as well as pain in your lower back and the sensation of a full rectum while during urination. Prostatitis can be classified into:

  1. Chronic prostatitis – is the most common type, with symptoms that come and go over time.

  2. Acute prostatitis - is characterised by severe and sudden symptoms; it is uncommon but potentially fatal, may come with fever and need immediate treatment.



4. Have hematuria (blood in the urine) or hematospermia (blood in semen) - The enlarged prostate, pinches the urethra and can sometimes lead to detection of blood in urine or sperm, too.



5. Erectile dysfunction - Prostatitis pain can cause sexual dysfunction, including erectile dysfunction and ejaculatory disturbance.



6. Feels like the bladder is never empty - Incomplete bladder emptying occurs when the muscles of the bladder are not able to squeeze properly to empty the bladder or due to an enlarged prostate gland that blocks the flow of urine out of the bladder.



If you see any of the above signs and symptoms, do immediate see your doctor right away for an early diagnosis of whether are you having prostate problems.


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3 min read

How does Melatonin Influence Your Body's Internal Clock?



The hormone of darkness - Melatonin


Melatonin is a hormone produced by the pineal gland in the brain that helps you fall asleep by triggering feelings of drowsiness. Melatonin levels rise in reaction to darkness, coordinating with the circadian rhythm (a 24-hour cycle that governs physical activities) to prepare your body for the first stage of sleep, awake. Sleep quality can be harmed by low melatonin synthesis, making it difficult to fall asleep. Night shift workers, those with sleep disorders, and frequent travellers may have sleep disruptions and poor sleep quality, which can be connected to melatonin deficiency.


What regulates melatonin production?


The suprachiasmatic nucleus (SCN) in the brain's hypothalamus regulates melatonin release by coordinating the timing of biological activities. The SCN, which is located above the optic nerves that connect your brain to your eyes, determines however much melatonin it secretes based on the amount of light entering your eyes. When it gets darker outside, your body produces more melatonin, which makes you sleepy. If your circadian clock is out of whack, your body may produce irregular melatonin throughout the day, causing sleep-wake cycles to be disrupted or sleep disorders to develop.


The consequences of melatonin deficiency in the human body


Poor sleep quality

When it comes to enhancing your performance and concentration, sleep is one of the most significant components. Melatonin, the sleep hormone, plays an important role in your sleep. Restlessness, a poor stress reaction, sleeplessness, and waking up too early in the morning can all be indicators of a deficit.


Stress & anxiety

Cortisol (a stress hormone) levels are at their lowest around midnight, according to research. They will begin to rise two to three hours after you go to bed and will continue to rise throughout the night as you wake up. This demonstrates an inverse relationship between melatonin production and release and cortisol:

  • The levels of cortisol in the body decrease as the levels of melatonin in the body rise.

  • As the body's melatonin levels fall, the body's cortisol levels rise.

Thus, a person with a low melatonin level will tend to have a higher stress response & have a risk of an anxiety incidence.


Besides that, Melatonin also aids in the physiological stress response. During the stress response, the body's temperature, blood pressure, and hormone levels all rise. Melatonin is important in the regulation of these physiological factors, which assists the body in relieving stress.


Weaker Immune

Melatonin sends signals to the immune system, and the immune system "talks" back, according to researchers. This "cross-talk" helps to fine-tune and coordinate healthy immunity. It strengthens innate defences against a wide range of pathogens, including viruses and cancer cells.


Melatonin enhances the body's immunity in several ways:

  • Improving the responses of antibodies that "tag" specific viruses, bacteria, and other invaders to be attacked by various immune system components,

  • Reducing chronic inflammation, which is the root cause of nearly all age-related chronic diseases

  • Increasing T cell activity, which aids in the more efficient destruction of pathogens.


Accelerated ageing process


Melatonin aids in the slowing of the ageing process in tissues such as the brain. It protects all tissues in the body because of its' powerful antioxidant property.


Is synthetic melatonin supplement your preferred option?


Melatonin supplements are not authorised for sale over the counter in countries like the UK, Ireland and also in Malaysia. Melatonin is a prescription-only medicine in these countries due to the fact that melatonin is a type of hormone. Even though in some other countries it is available to buy in health food shops or online.


When you supplement a hormone (melatonin), you are interfering with your own body's biosynthesis process, which many people cannot tolerate, resulting in a lot of dreams and dizziness in the morning. The common side effects of synthetic melatonin include:

  • feeling sleepy or tired in the daytime

  • headache

  • stomach ache or feeling sick (nausea)

  • feeling dizzy

  • feeling irritable or restless

  • dry mouth

  • dry or itchy skin

  • pains in your arms or legs

  • strange dreams or night sweats


Maize-derived ingredient, a safer alternative to synthetic melatonin


Maizinol, a natural ingredient derived from corn leaves (Zea mays), acts via the melatonin pathway. Its active compound is structurally similar to melatonin, binds with the receptors and boosts the body's own melatonin biosynthesis, without having adverse effects like synthetic melatonin.


Maizinol was found to assist with sleep & stress-related symptoms. A clinical study showed the ingredient significantly increased deep-sleep time by 30 minutes when taken before bed. It has also shown a significant reduction (~30%) in cortisol levels in the early morning.


Maizinol is marketed under the brand The PrimAGE ReszGuard in Malaysia.


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4 min read

6 Men's Health Concerns You Should Be Aware Of



Health is not a gender-specific issue. While it is important for everyone, regardless of age or gender, to get preventive health checks and make healthy dietary and lifestyle choices, multiple studies have shown that men are more likely to ignore health problems or be hesitant to see a doctor, often hiding problems because they believe they are already-fit and healthy. However, feeling healthy isn't always the same as actually being healthy, and ignoring problems until they worsen can make matters worse. Not only is it a big risk to take, but there are some specific symptoms and warning signs of deteriorating health that men should be aware of. We outline six common men's health issues and how to deal with them in this article.


1. Testosterone deficiency or ‘manopause’


Low testosterone affects millions of men, and the number is growing every year. Testosterone deficiency, also known as andropause or 'manopause', mimics many of the symptoms associated with female menopause. It affects men between the ages of 30 and 90, however, the good thing is not every man will get it, and for a large number of those who are affected, the symptoms are often downplayed or simply attributed to working too hard or having a mid-life crisis.


Common symptoms include tiredness, falling asleep after food, decreased libido, increased body fat/decreased muscle, poor concentration/brain fog, and increased irritability. In the later stages, men may also experience night sweats, changes in cholesterol and blood pressure, increased risk of diabetes, and osteoporosis (bone thinning).


You may check the testosterone score by answering a simple questionnaire or via a blood test to find out the total testosterone and free testosterone level. Fixing the cause with lifestyle changes (e.g. exercise), supplementation or starting testosterone replacement therapy (TRT) can be life-changing, lowering the risk of other serious medical problems, improving quality of life, and saving jobs, marriages, and families.



2. Prostate disease


Because women do not have prostate glands, this disease can only affect men. The prostate is a small gland behind the penis. It secretes fluids that are necessary for the release of sperm during sexual intercourse.


The prostate is prone to enlargement in men as they age. Its prevalence is incremental as men get older, with estimates of approximately 50% of men between the ages of 51 and 60, and up to 90% of men older than 80 being affected.



Another prostate-related issue is prostate cancer. It is said that if we live long enough, all men will develop some form of prostate cancer. It is the most common cancer in men, accounting for one-quarter of all cancer cases.


You can slow down prostate enlargement and reduce your risk of prostate cancer by not being overweight, exercising regularly, considering saw palmetto, pumpkin seed oil and lycopene supplementation, and getting regular health checks.


3. Erectile dysfunction (ED)


ED affects roughly half of all men at some point in their lives, but it is still a taboo subject. Men develop ED for a variety of reasons, including neurological or metabolic causes (such as diabetes), anxiety or stress, hormone deficiencies, or a narrowing of the blood supply to the penis. This last cause is so significant that it is widely accepted that if you have ED due to a vascular cause, you have about three years before it affects your heart (resulting in a heart attack). The penis is a health indicator. Phosphodiesterase (PDE) inhibitors pills such as sildenafil, and tadalafil can be effective in treating ED, but only if the underlying cause is identified.


4. Heart-Related Diseases


Heart disease, stroke, and artery diseases are among the top ten men's health issues worldwide. These conditions are referred to as cardiovascular diseases.

To avoid death from cardiovascular disease, you should have a regular medical check-up once every six months or yearly. You should also keep an eye on your blood pressure and adopt healthy habits like routine exercise and consuming more fruits and vegetables.


5. Lung Cancer and Respiratory Diseases


Lung cancer is a terrible disease because it can spread quickly before you notice any symptoms. Lung cancer can kill within a year of being diagnosed. Smoking is the leading cause of lung cancer in men. While the number of men who smoke has decreased, it is still a leading cause of death in men.


Unfortunately, there is no early detection test for lung cancer. The best way to avoid the disease is to quit smoking. If you are or have ever been a chronic smoker, see your doctor for a regular medical examination.


6. Diabetes


Diabetes develops when the level of glucose in your blood rises to dangerously high levels. It occurs when the pancreas fails to produce enough insulin or the body fails to respond to it. This results in an excess of glucose in the blood.


The frequent urge to urinate and excessive thirst are two major symptoms of diabetes. Diabetes develops gradually, and most men are unaware of it until they notice the first two major symptoms.


Excess glucose in the bloodstream can lead to a variety of diseases, including strokes, heart attacks, and blindness. Obese and overweight men are more likely to develop diabetes.


To prevent this disease, you should exercise for at least 30 minutes per day and eat a well-balanced diet rich in macronutrients.


Take early action to address the top men's health issues


If you've noticed any of the above-mentioned symptoms, do seek immediate medical attention. It is always better to guard your health, starting from the first sign.


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